PREPARATION OF d(-)-GLUTAMIC ACID FROM dl-GLUTAMIC ACID BY ENZYMATIC RESOLUTION

Glutamic Acid Dehydrogenase and Glutamic-oxalacetic

As part of a larger project dealing with an in vestigation of amino acid and protein metabolism in leukemia, a study was undertaken to determine those enzymes concerned with amino acid anabo lism and catabolism as they occur in selected tis sues. Several review papers (@,4, 11, 1@)have ade quately summarized our present knowledge of the metabolism of white blood cells (WBC) in leuke mia. Howeve...

Determination of Glutamic Acid

Synthesis and enzymatic hydrolysis of glutamic acid polypeptides.

Synthetic lysine polypeptides of high molecular weight (1) have been shown to reduce virus infectivity (2, 3), inhibit bacterial growth and respiration (4), agglutinate virus particles, bacterial cells, and erythrocytes (4-6), and to prolong blood clotting time (7). It has been suggested that most of these phenomena are associated with the formation of many ionic bonds between the positively ch...

Enzymatic Synthesis of y=Glutamylhydroxamic Acid from Glutamic Acid and Hydroxylamine*

The synthesis of y-glutamylhydroxamic acid from glutamine and hydroxylamine is catalyzed by glutamine synthetase in the presence of adenosine diphosphate, inorganic phosphate, and magnesium ions (l), and also by other enzyme preparations (2,3) that do not exhibit a requirement for nucleotides or metal ions. The synthesis of y-glutamylhydroxamic acid from glutamic acid and hydroxylamine that is ...

Enzymatic Synthesis of Gamma-glutamylhydroxamic Acid from Glutamic Acid and Hydroxylamine.

The synthesis of y-glutamylhydroxamic acid from glutamine and hydroxylamine is catalyzed by glutamine synthetase in the presence of adenosine diphosphate, inorganic phosphate, and magnesium ions (l), and also by other enzyme preparations (2,3) that do not exhibit a requirement for nucleotides or metal ions. The synthesis of y-glutamylhydroxamic acid from glutamic acid and hydroxylamine that is ...